Gridlock'd (1997)

Two addicts wander around Detroit under the influence as they try to seek help with their addiction. Both hilarious and a serious comment on society.

On new year's eve Spoon and Stretch drop their friend off at the hospital after she overdoses and make the decision to deal with their own addictions, but only after taking one more hit. As they move from one government office to another they are haphazardly embroiled in more and more trouble with a drug lord and the police. Their lives are saved and their efforts thwarted at every turn.

The acting in the film is brilliant. Tim Roth and Tupac Shakur demonstrate agility in their comedy and drama. Gridlock'd also contains a most hilarious stabbing scene.

IMDB